Print

Chicken Bubble Biscuit Bake Casserole Recipe

4.4 from 107 reviews

Chicken Bubble Biscuit Bake Casserole is a comforting, easy-to-make one-dish meal combining tender shredded chicken, creamy sauce, mixed vegetables, and fluffy biscuit dough baked to golden perfection. This casserole is perfect for busy weeknights or casual family dinners, delivering a delicious blend of creamy, savory flavors topped with cheesy biscuits that bubble up during baking.

Ingredients

Scale

Chicken Mixture

  • 2 cups cooked chicken, shredded or diced (rotisserie chicken works great)
  • 1 10.5 oz can cream of chicken soup (or cream of mushroom soup)
  • 1/2 cup sour cream or plain Greek yogurt
  • 1/2 cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn, beans)
  • 1 tsp garlic powder
  • 1/2 tsp onion powder
  • Salt & pepper to taste

Biscuit Topping

  • 1 16 oz can refrigerated biscuit dough, cut into quarters
  • 1 cup shredded cheddar cheese or mozzarella cheese
  • 1 tbsp melted butter (optional, for brushing)

Instructions

  1. Prepare the Chicken Mixture: In a large bowl, combine the shredded cooked chicken, cream of chicken soup, sour cream or Greek yogurt, milk, frozen mixed vegetables, garlic powder, onion powder, salt, and pepper. Mix thoroughly until all ingredients are well incorporated.
  2. Transfer to Baking Dish: Pour the chicken and vegetable mixture into a greased casserole dish, spreading it out evenly to form the base layer.
  3. Add Biscuit Topping: Cut the refrigerated biscuit dough into quarters and arrange the pieces on top of the chicken mixture evenly. Sprinkle the shredded cheddar or mozzarella cheese evenly over the biscuit pieces. Optionally, brush the biscuit tops with melted butter for a golden, crisp finish.
  4. Bake the Casserole: Preheat your oven to 375°F (190°C). Place the casserole dish on the middle rack and bake uncovered for 25 to 30 minutes or until the biscuits are golden brown and cooked through, and the filling is bubbly and hot.
  5. Cool and Serve: Remove from the oven and allow the casserole to cool slightly before serving. This helps the casserole to set and makes it easier to portion.

Notes

  • You can substitute cream of chicken soup with cream of mushroom or cream of celery soup for a different flavor.
  • Use Greek yogurt as a healthier alternative to sour cream.
  • Add more or different vegetables according to preference or what’s available.
  • Rotisserie chicken saves time and adds great flavor, but any cooked chicken works well.
  • Melted butter on the biscuit topping enhances browning, but it’s optional.
  • For a lower calorie option, use reduced-fat cheese and yogurt.

Keywords: chicken casserole, biscuit bake, comfort food, easy dinner, one dish meal, creamy chicken bake, mixed vegetable casserole